Phn Quality Products

Chlorphenamine 

 
 
Chlorphenamine 4mg

Chlorphenamine (INN) or chlorpheniramine (USAN, former BAN), commonly marketed as its salt chlorphenamine maleate (CPM; Chlor-Trimeton, Piriton, Chlor-Tripolon), is a first-generation alkylamine antihistamine used in the prevention of the symptoms of allergic conditions such as rhinitis and urticaria. Its sedative effects are relatively weak compared to other first-generation antihistamines. Chlorpheniramine is one of the most commonly used antihistamines in small-animal veterinary practice as well. Although not generally approved as an antidepressant or anti-anxiety medication, chlorpheniramine appears to have these properties as well (see below).

Chlorpheniramine is part of a series of antihistamines including pheniramine (Naphcon) and its halogenated derivatives and others including fluorpheniramine, dexchlorpheniramine (Polaramine), brompheniramine (Dimetapp), dexbrompheniramine (Drixoral), deschlorpheniramine, dipheniramine (also known as triprolidine with the trade name Actifed), and iodopheniramine.

The halogenated alkylamine antihistamines all exhibit optical isomerism, and chlorpheniramine in the indicated products is racemic chlorpheniramine maleate, whereas dexchlorpheniramine (Polaramine) is the dextrorotary stereoisomer

BRAND NAME: Zyrtec
DRUG CLASS AND MECHANISM: Cetirizine is the fourth addition to a new generation of allergy medications called "non- sedating" antihistamines or histamine (H-1) receptor blockers. These new antihistamines are called non-sedating because they cause less sedation than their predecessors; however, cetirizine is more sedating than the other non-sedating antihistamines.

Antihistamines block the effects of histamines. Histamines cause symptoms of allergy when released by allergic reactions in the body. Antihistamines block the ability of histamine to promote the allergy symptoms. For further information, please read the Allergic Rhinitis article.

PRESCRIPTION: Yes

GENERIC AVAILABLE: Yes

PREPARATIONS: 5mg and 10mg oral tablets.

STORAGE: Store in a dry place at 15-30 degrees C (59- 86 F).

PRESCRIBED FOR: Cetirizine is used by people who suffer from allergic symptoms such as sneezing, itchy nose (allergic rhinitis) and itchy eyes. It also has been used to treat hives.

DOSING: Cetirizine should be taken at doses specifically directed by a physician. Cetirizine can be taken with food.

DRUG INTERACTIONS: Cetirizine should be taken only in doses prescribed. Increasing the dose can be dangerous. When taking cetirizine with theophylline the dose of theophylline may need to be reduced. Cetirizine occasionally can cause sleepiness . Cetirizine can be taken with erythromycin or ketaconazole without the increased risk of heart irregularities common to other non-sedating antihistamines. Cetirizine also can be used to treat children.

SIDE EFFECTS: Sleepiness occurs in 14% of patients. Dry mouth, nausea, headache, fatigue, jitteriness and sore throat are infrequently reported with cetirizine.